Pneumology

Publications

  • Beyeler S, Chortarea S, Rothen-Rutishauser B, Petri-Fink A, Wick P, Tschanz SA, von Garnier C, Blank F. Acute effects of multi-walled carbon nanotubes on primary bronchial epithelial cells from COPD patients.Nanotoxicology. 2018 May 26:1-13.
  • Leffler J, Mincham KT, Mok D, Blank F, Holt PG, Stumbles PA, Strickland DH.Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization. Immunol Cell Biol. 2018 Mar;96(3):316-329.
  • Gazdhar A, Blank F, Cesson V, Lovis A, Aubert JD, Lazor R, Spertini F, Wilson A, Hostettler K, Nicod LP, Obregon C. Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/FLT3 Monocytes That Promote Allogeneic Th17 Differentiation. Front Immunol. 2017 Apr 25;8:447.
  • Blom RAM, Amacker M, van Dijk RM, Moser C, Stumbles PA, Blank F, von Garnier C. Pulmonary Delivery of Virosome-Bound Antigen Enhances Antigen-Specific CD4+ T Cell Proliferation Compared to Liposome-Bound or Soluble Antigen. Front Immunol. 2017 Apr 7;8:359.
  • Blom RAM, Amacker M, Moser C, van Dijk RM, Bonetti R, Seydoux E, Hall SRR, von Garnier C, Blank F. Virosome-bound antigen enhances DC-dependent specific CD4+ T cell stimulation, inducing a Th1 and Treg profile in vitro. Nanomedicine. 2017 Jul;13(5):1725-1737.
  • Blank F, Fytianos K, Seydoux E, Rodriguez-Lorenzo L, Petri-Fink A, von Garnier C, Rothen-Rutishauser B. Interaction of biomedical nanoparticles with the pulmonary immune system. J Nanobiotechnology. 2017 Jan 9;15(1):6. doi: 10.1186 s12951-016-0242-5. Review
  • Seydoux E, Rodriguez-Lorenzo L, Blom RA, Stumbles PA, Petri-Fink A, Rothen-Rutishauser BM, Blank F, von Garnier C. Pulmonary delivery of cationic gold nanoparticles boost antigen-specific CD4+ T Cell Proliferation. Nanomedicine. 2016 Oct;12(7):1815-1826
  • Blom RA, Erni ST, Krempaská K, Schaerer O, van Dijk RM, Amacker M, Moser C, Hall SR, von Garnier C, Blank F. A Triple Co-Culture Model of the Human Respiratory Tract to Study Immune-Modulatory Effects of Liposomes and Virosomes. PLoS One. 2016 Sep 29;11(9):e0163539.
  • von Garnier C, Blank F, Rothen-Rutishauser B, Goethert JR, Holt PG, Stumbles PA, Strickland DH.Identification and Characterization of a Dendritic Cell Precursor in Parenchymal Lung Tissue. Am J Respir Cell Mol Biol. 2016 Oct 25.
  • Fear VS, Lai SP, Zosky GR, Perks KL, Gorman S, Blank F, von Garnier C, Stumbles PA, Strickland DH. A pathogenic role for the integrin CD103 in experimental allergic airways disease. Physiol Rep. 2016 Nov;4(21). pii: e13021.
  • Seydoux E, Rothen-Rutishauser B, Nita IM, Balog S, Gazdhar A, Stumbles PA, Petri-Fink A, Blank F, von Garnier C. Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation. Int J Nanomedicine. 2014 Aug 13;9:3885-902.
  • Seydoux E., Rothen-Rutishauser B., Nita IM., Balog S., Gazdhar A., Stumbles PA., Petri-Fink A., Blank F., von Garnier C. Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation. Int J Nanomed. In press.
  • Blank F, Stumbles PA, Seydoux E, et al. Size-dependent Uptake of Particles by Pulmonary APC Populations and Trafficking to Regional Lymph Nodes. Am J Respir Cell Mol Biol. 2013;49:67–77.
  • Blank F, Gerber P, Rothen-Rutishauser B, et al. Biomedical nanoparticles modulate specific CD4(+) T cell stimulation by inhibition of antigen processing in dendritic cells. Nanotoxicology. 2011;5:606–21.
  • Von Garnier C, Nicod LP. Immunology taught by lung dendritic cells. Swiss Med Wkly. 2009;139(13-14):186–92.
  • Blank F, von Garnier C, Obregon C, Rothen-Rutishauser B, Gehr P, Nicod L. Role of dendritic cells in the lung: in vitro models, animal models and human studies. Expert Rev Respir Med. 2008;2(2):215–33.
  • Von Garnier C, Wikstrom ME, Zosky G, Turner DJ, Sly PD, Smith M, Thomas JA, Judd SR, Strickland DH, Holt PG, Stumbles PA. Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa. J Immunol. 2007 Nov 1;179(9):5748-59.
  • Blank F, Rothen-Rutishauser B, Gehr P. Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens. Am J Respir Cell Mol Biol. 2007;36(6):669–77.
  • Von Garnier C, Filgueira L, Wikstrom M, et al. Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract. J Immunol. 2005;175(3):1609–18.